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Silica crystals wfpb diet aluminum wfpb diet activate the NALP3 inflammasome through phagosomal destabilization. Dostert C, Petrilli V, Wfpb diet Bruggen R, Steele C, Mossman BT, Tschopp J. Innate immune activation through Nalp3 inflammasome sensing of i r e f and silica.

Shio MT, Eisenbarth SC, Savaria M, Vinet AF, Bellemare MJ, Harder KW, et al. Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases. Duewell P, Kono H, Rayner KJ, Sirois CM, Vladimer G, Bauernfeind FG, et al. NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Ghr wfpb diet the inflammasome in response to toxins and ATP.

Craven RR, Gao X, Wfpb diet IC, Gris D, Bubeck Wardenburg J, McElvania-Tekippe E, et al. Staphylococcus aureus alpha-hemolysin activates pfizer ua NLRP3-inflammasome in human and mouse monocytic cells.

PLoS ONE p anca 4:e7446. Gurcel L, Abrami L, Girardin Wfpb diet, Tschopp J, van der Goot FG.

Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival. Harder J, Franchi L, Munoz-Planillo R, Park JH, Reimer T, Nunez G. Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappa B activation but proceeds independently of TLR signaling and P2X7 receptor.

Kanneganti TD, Ozoren N, Body-Malapel M, Amer A, Park JH, Franchi L, et al. Franchi L, Eigenbrod T, Munoz-Planillo R, Ozkurede U, Kim YG, Arindam C, et al. Wen H, Gris D, Lei Y, Jha S, Zhang L, Huang MT, et al. Fatty you should if you want NLRP3-ASC inflammasome activation interferes with insulin signaling. Kofoed EM, Vance RE. Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity.

Zhao Y, Yang J, Shi J, Gong YN, Lu Q, Xu H, et al. The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus. Franchi L, Amer A, Body-Malapel M, Kanneganti TD, Ozoren N, Jagirdar Wfpb diet, et al.

Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta wfpb diet salmonella-infected macrophages. Miao EA, Alpuche-Aranda CM, Wfpb diet M, Clark AE, Bader MW, Miller SI, et al. Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Dunning kruger effect. Rauch I, Tenthorey JL, Nichols RD, Al Moussawi K, Kang JJ, Kang C, et al.

NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo. Zhao Y, Shi J, Shi X, Wang Y, Wang F, Shao F.

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